人生100年時代を見据えた
肥満症学の新展開
〜協奏と創造〜
The 43rd Annual Meeting of the Japan Society for the Study of Obesity
International Satellite Symposium
The 5Gs on Obesity and Diabetes Research
We are pleased to announce that the International Satellite Symposium of the 43rd Annual Meeting of the Japan Society for the Study of Obesity, “The 5Gs on Obesity and Diabetes Research” will be held on Thursday, December 1, 2022 at the Hotel Collective in Naha city, Okinawa.
The molecular mechanisms of energy balance and body weight regulation are coming to light by the recent robust progresses in the molecular biology and neuroendocrine researches. The gastrointestinal treat produces a large array of peptides to regulate energy homeostasis. Recent advances in peptide-engineering techniques have developed new classes of drugs to alleviate impaired energy balance and body weight. The 5Gs (GLP-1, GIP, Ghrelin, Glucagon and other Gut hormones) are inspiring the pursuit of next-generation drugs in obesity and diabetes. In addition to hormonal actions of peptides in cell-cell communication, recently accumulated knowledge based on these 5Gs indicates that peptides produced in the periphery send their signals to the brain via the vagal sensory nerve.
We are confident that this symposium will contribute to extend our better understanding of obesity and diabetes and their conquest.
- Masamitsu Nakazato
- University of Miyazaki/ Osaka University
- Hiroaki Masuzaki
- University of the Ryukus
- Masayuki Ohta
- Oita University
Agenda
December 1, 2022
Hotel Collective 2F Medium Banquet Hall
2-5-7 Matsuo Naha-city
Okinawa 900-0014, Japan
https://hotelcollective.jp/
- 12:10 ‒ 12:20
-
- Opening Remarks
- Masamitsu Nakazato (University of Miyazaki/ Osaka University)
- 12:20 ‒ 13:50
-
- Session 1 (3 speakers)
- Chair:Takayoshi Suganami(Department of Molecular Medicine and Metabolism, Research Institute of Environmental Medicine, Nagoya University)
- Chair:Naoto Kubota (Department of Diabetes and Metabolic Diseases Graduate School of Medicine, University of Tokyo)
- “Chronology of islet cell genesis for curing diabetes”
Takeshi Miyatsuka (Kitasato University School of Medicine / Juntendo University Graduate School of Medicine) - “NAMPT-mediated NAD+ biosynthesis in intestinal epithelium regulates GLP-1 production and postprandial glucose levels in mice”
Shintaro Yamaguchi (Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine) - “An Enigma of 69 Years: Function of Glucose-Sensing Neurons in the Brain”
Greg Seong-Bae Suh (Department of Biological Sciences, KAIST Daejeon, South Korea)
- 13:50 ‒ 14:05
-
- Break
- 14:05 ‒ 15:35
-
- Session 2 (3 speakers)
- Chair:Hideki Katagiri (Department of Metabolism and Diabetes, Tohoku University Graduate School of Medicine)
- Chair:Toshimasa Yamauchi (Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo)
- “Optimizing cryo-EM for GPCRs and first steps in cryo-tomography”
Radostin Danev (The University of Tokyo, Japan) - “Semaglutide as a centrally acting regulator of appetite”
Anna Secher (Global Drug Discovery, Novo Nordisk A/S) - “Tirzepatide Modulates Caloric Intake and Energy Expenditure in Diet-Induced Obese Mice”
Tamer Coskun (Eli Lilly and Company, U.S.A)
- 15:35 ‒ 15:50
-
- Break
- 15:50 ‒ 16:50
-
- Session 3 (2 speakers)
- Chair:Koshi Hashimoto (Department of Diabetes, Endocrinology and Hematology Dokkyo Medical University Saitama Medical Center)
- Chair:Norikazu Maeda (Department of Metabolism and Atherosclerosis, Graduate School of Medicine, Osaka University)
- “Dynamic changes of the 5Gs by metabolic surgery and the 5Gs’ important role for improving comorbidities”
Akira Umemura (Department of Surgery, Iwate Medical University School of Medicine) - “Role of GIP in high-fat diet-induced obesity and insulin resistance”
Norio Harada (Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University)
- 16:50 ‒ 16:55
-
- Closing Remarks
- Hiroaki Masuzaki (University of the Ryukyus Graduate School of Medicine)
JASSO, JSTO Member/JPY 1,000
Non-Member/JPY 2,000
Students/Graduate students Free